While MALDI MSI has thus far been most heavily utilized in the fields of pharmacology, analytical chemistry, and "omics" level studies, this technology offers tremendous opportunities in the field of forensic science as well. MALDI MSI can be used to examine a variety of types of evidence, such as fingerprints, hair, and fibers, from crime scenes at a deep biomolecular level while preserving important patterns in the analytical data that may be important factors in the events leading up to a crime.
It is essential that forensic researchers utilize highly effective analytical techniques that produce results with the highest level of confidence so that evidence can be upheld in court. Thanks to the large dynamic range of MALDI mass spectrometers, researchers are able to analyze a wide range of compounds in unknown samples. Information on both endogenous and exogenous compounds can be obtained in a single experiment without extensive sample separation and preparation.