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App Note #45

Investigating Metabolic Changes in Salinity-Stressed Barley Roots

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App Note #44

Mass Spectrometry Imaging of Moss, Fungus, and Cyanobacteria on Agar

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App Note #43

Updated Enzymatic Digestion Protocol...Coming Soon!!!

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App Note #42

IMS to Investigate Age-Related Renal Toxicity of RAF Inhibitor, Dabrafebnib 

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App Note #41

Effects of Tray  Temperature  on  Matrix Deposition and IMS Image Quality

App Note #40

Using MALDI IMS to Re-diBacterial Biofilm Heterogeneity

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App Note #39

MALDI FTICR: Spatial Proteomics of Cystic Fibrosis Lungs

App Note #38

Linking m/z Protein Images with Proteomics data

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App Note #37

SepQuant dropletProbe™️: Automated LESA Technology

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App Note #36

Spray Application of DHB on Dried Agar for MALDI Imaging of Microbial Cultures

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App Note #35

High-Resolution MALDI MSI of Lipids in Rat Brain Tissue in + and - Mode

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App Note #34

Sublimation-like Results of Dry Matrix Application: IMS of Plant Metabolites

App Note #32

Analysis of Latent Fingermarks by MALDI IMS

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App Note #31

Matrix Deposition Optimization: Improve detection; Reduce delocalization

App Note #30

Whole Body Imaging: Localization of parent drugs and metabolites in tissues

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App Note #29

MALDI MSI of Lipids in Rat Brain Tissue in Positive and Negative Mode

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App Note #28

Optimization of DHB Matrix Spray for MALDI Imaging of Plant Metabolites.

App Note #27

Demonstration of trypsin spray deposition for in-tissue digestion.

 
 
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HTX TM-Sprayer™️

M3 Model: MALDI Sample Preparation System 

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HTX M5 Sprayer™️

M5 Model: Advanced MALDI Sample Preaparation System

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HTX SepQuant dropletProbe™️

Liquid Extraction for Surface Sampling & Analysis

 
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High-mass-resolution MALDI mass spectrometry imaging reveals detailed spatial distribution of metabolites and lipids in roots of barley seedlings in response to salinity stress. 

Sarabia, et al. ~ Metabolomics 2018

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The genome of Chenopodium quinoa

Jarvis, et al. ~ Nature 2017

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A multi-omics strategy resolves the elusive nature
of alkaloids in
Podophyllum species

Marques, et al. ~ Molecular BioSystems 2014

 
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MALDI imaging of 

on-tissue digests at 

high spatial resolution 

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Investigating MALDI Fundamentals with TOF-SIMS 

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In-Depth ID of proteins

 
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Robust Sample Preparation with HTX TM-Sprayer

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Improvements in MSI for the Molecular Analysis of FFPE Tissue Sections

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Biomarker Monitoring by Quantitative IMS

 
 
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Global lipidomic changes associated with MALDI matrices using MALDI FT-ICR IMS

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High Resolution Accurate Mass Imaging by MALDI FT-ICR

 
 
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Spatial Mapping of Fungal Secondary Metabolites

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Profiling ACTH & AVP in Human Pituitary Gland Sections

 
 
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In Situ Characterization of Bioactive Secondary Metabolites