MALDI Mass Spectrometry Imaging (MSI) allows for scientists to visualize the spatial distribution of peptides and proteins. Each experiment creates many images and allows for investigators to visualize multiple species at once. The MALDI source is especially well suited to proteomics because large molecules such as proteins and peptides are prone to damage by harsher ionization sources.
Matrix application is a critical step in MALDI mass spectrometry imaging of proteins and peptides due to the need to extract the analytes from tissue without sacrificing image resolution. The HTX MALDI matrix Sprayers are ideal sample preparation instruments for proteomics MALDI MSI work as they allow you to perform trypsin digestion and matrix application using one instrument.